The passenger in the crash on the 405 has died in hospital.
The OPP says 74-year-old Gilbert Dunk of Burlington was taken to hospital with life-threatening injuries on Wednesday afternoon.
The single vehicle crash happened in the U.S. bound lanes at the Queenston-Lewiston bridge.
Seventy-three-year-old Alan Ashton of Burlington was driving the vehicle.
He was also killed.
Police are sending their condolences to the victims families.
Province Investing Against Invasive Species
The $2-million will help the Niagara region
Niagara Driver Charged with Drug Impairment
OPP say this happened on Highway 17, when a car was seen weaving all over the road
Welland Man Arrested for Child Porn
Police say they noticed child sexual abuse material shared on a social media page early this month
28 More Doctors Hired in Niagara
The region and Niagara Health coordinating new partnership to find even more doctors
Killed Police Officers Honoured by NRP
Police Chief praised Niagara members for standing at attention in 'pounding rain'
Niagara Wineries Shuttle Service Possible
The CUTRIC hopes the province supports helping people move among wineries
Canal Days Vendors Warned of Scams
The City of Port Colborne says criminals are sending fraud emails for payment
Niagara Falls Exploring Hub to Help Homeless
Former CAO Ken Todd has been meeting with community groups