Niagara Regional Police responded to the Central Avenue QEW Overpass for a report of a person in distress.
Officers got there just before 11:00 a.m. on Saturday.
Shortly after police arrived, the 28-year-old man fell from the bridge and was taken to an out-of-town hospital with serious but non life threatening injuries.
The Special Investigation Unit has started an investigation into the situation.
NRP Investigating Fatal Pelham Crash
This happened last night on Highway 20
NRP Officers Praised by Management
Chief wishes the public could see the professionalism
945 Supportive Housing Units Approved
The region working to help the homeless
Niagara Talks Canadian Defense
It was how to contribute to Canada's defense
Niagara Falls Expecting More Evacuees
NRP says flooding season approaching
St. Catharines Man Charged with Voyuerism
Police say he filmed women at Welland mall
Candidate Registration Approaches
This is for the fall municipal election
Niagara Parks Getting New Police Chief
The change in leadership comes in June.