Season opener September 12th at home
Bills fans mark this down on your calendar.
The 2021 NFL schedule has been revealed and the Bills will kickoff the season at home September 12th at 1:00 against the Steelers
Two of four primetime games will be on a Monday night, one at home against the Patriots and the other on the road in Tennessee.
The first preseason game will be August 13th when the Bills travel to Detroit to take on the Lions.
The 2021 NFL season will see each team play 17 regular season games and three preseason contests.
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